What we do

 

We provide high‑impact consultancy across the full vaccine and viral vector development chain:

 

 

• R&D, Innovation and Manufacturing (GMP) management.

 

• Business development and Academic network building.

 

• Vaccine process design and optimization (Sabin‑IPV, Salk‑IPV, rotavirus, adenoviral vectors and other viral platforms).

 

• Bioprocess engineering and scale-up, including bioreactor selection (stirred, rocking, fixed‑bed, air‑lift), hydrodynamics, mass/oxygen transfer and mixing.

 

• Cell line and platform selection for viral vaccine and vector production (Vero, PER.C6, CHO, HEK293 and other host systems).

 

• Data‑driven process understanding (multivariate data analysis, kinetic modeling of adherent Vero cells and virus production, scale‑down models).

 

• Analytical strategy for viral vaccines (antigen assays, isoelectric focusing, in‑process ELISAs and critical quality attribute monitoring).

 

• Technology transfer and cost‑of‑goods reduction for emerging economies manufacturing sites, including animal‑component‑free processes, antigen‑sparing formulations and combination vaccine development.

 

• Support for pre‑clinical and clinical development (phase I/II study design input for IPV and other viral vaccines, interpretation of immunogenicity and safety data).

 

• Grant strategy and writing support based on a long-standing proven track-record in grant aquisition.

 

 

 

 

How we work

 

Bakker Biotech works in a flexible, collaborative model, integrating seamlessly with your project teams as an external partner or acting as an independent expert reviewer of your development strategy and technical dossiers. We can engage on short, focused assignments (e.g. troubleshooting a low‑yield step, evaluating a new cell line or bioreactor concept) or on longer programs that span from feasibility through tech transfer and early clinical stages. Our approach is pragmatic and data‑driven: we build on existing knowledge and historical data, identify critical gaps, and propose realistic, implementable solutions that fit your timelines, budgets and regulatory context.